منابع مشابه
A comparison of cholesteryl oleate and 19-iodocholesteryl oleate as substrates for adrenal cholesterol esterase.
Radiolabeled 19-iodocholesterol is widely used to obtain images of human adrenals. We have shown in rats and mice that 85-95% of the radiolabel is present in the esterified form. Using rat adrenal cytosolic cholesterol esterase, the kinetic parameters K~t and V were determined for commercially available cholesteryl [l-14C]-oleate (!) and [125I]-19-iodocholesteryl oleate (It). The Kra and V were...
متن کاملLDL cholesteryl oleate as a predictor for atherosclerosis: evidence from human and animal studies on dietary fat.
This review focuses on the relationships among dietary fat type, plasma and liver lipid, and lipoprotein metabolism and atherosclerosis. Dietary polyunsaturated fatty acids are beneficial for the prevention of coronary artery atherosclerosis. By contrast, dietary monounsaturated fatty acids appear to alter hepatic lipoprotein metabolism, promote cholesteryl oleate accumulation, and confer ather...
متن کاملConformation of the oleate chains in crystals of cholesteryl oleate at 123 K.
At 123 K, crystals of cholesteryl cis-9-octadecenoate (cholesteryl oleate, C45H78O2) are monoclinic, space group P2(1) with unit cell dimensions a = 12.356(2), b = 8.980(3), c = 18.382(2) A, beta = 85.49(2) degrees, and have two molecules in the unit cell. The crystal structure including all H atoms has been determined from 3812 independent X-ray reflections with sin theta/lambda less than 0.61...
متن کاملSolubilization of triolein and cholesteryl oleate in egg phosphatidylcholine vesicles.
The incorporation of cholesteryl oleate and triolein into phospholipid vesicles was studied in cosonicated mixtures of 94 weight % egg phosphatidylcholine and 6 weight % neutral lipid (0-6% triolein and 6-0% cholesteryl oleate). 13C NMR spectroscopy was used to quantitate both neutral lipids in vesicles containing 90% isotopically substituted [carbonyl-13C]cholesteryl oleate and [carbonyl-13C]t...
متن کاملExchange of oxidized cholesteryl linoleate between LDL and HDL mediated by cholesteryl ester transfer protein.
This study examines the cholesteryl ester transfer protein (CETP)-mediated exchange of cholesteryl linoleate hydroperoxide (Ch18:2-OOH) and cholesteryl linoleate hydroxide (Ch18:2-OH) between low density lipoprotein (LDL) and high density lipoprotein (HDL). When [3H]Ch18:2-OOH- and [3H]18:2-OH-labeled LDL were incubated at 37 degrees C for 0-24 h with unoxidized HDL and purified CETP, Ch18:2-OO...
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ژورنال
عنوان ژورنال: Arteriosclerosis, Thrombosis, and Vascular Biology
سال: 2007
ISSN: 1079-5642,1524-4636
DOI: 10.1161/atvbaha.107.147082