Layered Silicate-Alginate Composite Particles for the pH-Mediated Release of Theophylline
نویسندگان
چکیده
منابع مشابه
Theophylline-Ethylcellulose Microparticles: Screening of the Process and Formulation Variables for Preparation of Sustained Release Particles
Objective(s) The aim of this study was to formulate and evaluate microencapsulated controlled release preparations of theophylline using ethylcellulose as the retardant material with high entrapment efficiency. Materials and Methods Microspheres were prepared by water-in-oil-in-oil (W/O1/O2) emulsion-solvent diffusion (ESD). A mixed solvent system consisting of acetonitrile and dichloromet...
متن کاملtheophylline-ethylcellulose microparticles: screening of the process and formulation variables for preparation of sustained release particles
objective(s) the aim of this study was to formulate and evaluate microencapsulated controlled release preparations of theophylline using ethylcellulose as the retardant material with high entrapment efficiency. materials and methods microspheres were prepared by water-in-oil-in-oil (w/o1/o2) emulsion-solvent diffusion (esd). a mixed solvent system consisting of acetonitrile and dichloromethane ...
متن کاملPreparation and pH-Sensitive Release Behavior of Alginate/Activated Carbon Composite Magnetic Hydrogels
The alginate-based hydrogel was prepared as a pH-sensitive drug delivery system. To enhance the drug loading capacity, activated carbon was introduced as a drug absorbent. The iron oxide was incorporated into the alginate matrix for the magnetic transferring to the target organ. The activated carbon and iron-oxide were dispersed uniformly in the alginate hydrogel. The drug release from the algi...
متن کاملTheophylline-Ethylcellulose Microparticles: Screening of the Process and Formulation Variables for Preparation of Sustained Release Particles
OBJECTIVES The aim of this study was to formulate and evaluate microencapsulated controlled release preparations of theophylline using ethylcellulose as the retardant material with high entrapment efficiency. MATERIALS AND METHODS Microspheres were prepared by water-in-oil-in-oil (W/O1/O2) emulsion-solvent diffusion (ESD). A mixed solvent system consisting of acetonitrile and dichloromethane ...
متن کاملIn situ preparation and protein delivery of silicate-alginate composite microspheres with core-shell structure.
The efficient loading and sustained release of proteins from bioactive microspheres remain a significant challenge. In this study, we have developed bioactive microspheres which can be loaded with protein and then have a controlled rate of protein release into a surrounding medium. This was achieved by preparing a bioactive microsphere system with core-shell structure, combining a calcium silic...
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ژورنال
عنوان ژورنال: Pharmaceuticals
سال: 2020
ISSN: 1424-8247
DOI: 10.3390/ph13080182