LATS activity, exophthalmos and digital clubbing associated with myxoedema.

LATS activity, exophthalmos and digital clubbing associated with myxoedema.

RIACH, I.C.F. (1966) The Stella Index-A relationship between the area of the sella turcica and the lateral area of the skull. Brit. J. Radiol. 39, 824. SMrrH, D.W., BLiZZARD, R.M. & WILKINS, L. (1957) The mental prognosis in hypothyroidism of infancy and childhood. Pediatrics, 19, 1011. VON HARNACK, G.A. (1953) Eineiige Zwillinge mit diskordanter Hypothyreose. Arch. Kinderheilk, 146, 60. VON HA...

Digital clubbing.

Clubbing associated with oesophageal adenocarcinoma.

A patient with an oesophageal adenocarcinoma, recent onset of digital clubbing, and evidence of increased oestrogen synthesis is presented. In the discussion, some of the theories of the pathogenesis of clubbing are reviewed, together with previous reports of clubbing in gastro-oesophageal disorders. A possible unifying theory is proposed for our case which we believe is the first report of thi...

Progressive furrowing of skin with digital clubbing.

70 year old man with chronic obstructive pulmonary disease and hypertension was admitted to hospital with a two month history of worsening dyspnoea on exertion and ankle swelling. On examination, the patient was in atrial fibrillation with an apical ventricular rate of 136 beats/min. The jugular venous pressure was not visible , but there was bilateral pitting oedema to the knees. Auscultation ...

Autoimmune haemolytic anaemia and ulcerative colitis D. W. GORST

Kriss et al. (1964) postulated that the destruction of the thyroid gland by disease (hyperthyroidism or thyroiditis) or by therapeutic agents (especially 1311) results in the release of an antigen of thyroid cell origin which then stimulates the production of the antibody, LATS. The antibody is then fixed to the tissues of the legs, the phenomenon being facilitated by a number of factors such a...