Late-Onset Myasthenia Gravis

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Late-onset myasthenia gravis: a changing scene.

The prevalence of myasthenia gravis (MG) among middle-aged and older patients has increased. Patients with early-onset MG live longer than before, but there is also an increase in late-onset MG (onset of the disease after the age of 50 years in patients with no clinical or paraclinical evidence of a thymoma). Epidemiological data support using the age of 50 years to separate early- and late-ons...

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A new approach to late onset myasthenia gravis.

We have demonstrated that thymectomy alone can improve many patients with myasthenia gravis, including those with the late onset form of the disorder. A key advantage to this approach is that it avoids the necessity of concurrent medication. While a drug-free approach has advantages for any patient, it is particularly well suited for those over the age of 55. Based on the results of our study, ...

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Antititin antibody in early- and late-onset myasthenia gravis.

OBJECTIVES Myasthenia gravis (MG) is an autoimmune disease caused by antibodies against neuromuscular junction proteins, 85% of patients have antibodies against acetylcholine receptor (AChR-MG). Antititin antibodies are present in a subset of patients with MG. We aimed to determine the value of antititin antibodies as severity markers and thymoma predictors in early- and late-onset MG. MATERI...

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ژورنال

عنوان ژورنال: Archives of Neurology

سال: 1999

ISSN: 0003-9942

DOI: 10.1001/archneur.56.1.25