Lassa Fever: Another Infectious Menace
نویسندگان
چکیده
منابع مشابه
Lassa fever: another threat from West Africa
Lassa fever, a zoonotic viral infection, is endemic in West Africa. The disease causes annual wide spread morbidity and mortality in Africa, and can be imported by travelers. Possible importation of Lassa fever and the potential for the use of Lassa virus as an agent of bioterrorism mandate clinicians in Israel and other countries to be vigilant and familiar with the basic characteristics of th...
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The microbial world, since its origin, has conducted countless genetic experiments to better ensure adaptation and hence survival in its biologic niche. Through this trial and error process, “smart” parasites have learned that the ability to persistently infect without limiting the host’s survival ensures their own survival. The host is spared immediate demise, but we are just beginning to unde...
متن کاملPathogenesis of Lassa Fever
Lassa virus, an Old World arenavirus (family Arenaviridae), is the etiological agent of Lassa fever, a severe human disease that is reported in more than 100,000 patients annually in the endemic regions of West Africa with mortality rates for hospitalized patients varying between 5-10%. Currently, there are no approved vaccines against Lassa fever for use in humans. Here, we review the publishe...
متن کاملLassa Fever, Nigeria, 2005–2008
To the Editor: Lassa fever affects ≈100,000 persons per year in West Af-rica (1). The disease is caused by Las-sa virus, an arenavirus, and is associated with bleeding and organ failure. The case-fatality rate in hospitalized patients is 10%–20%. The reservoir of the virus is multimammate mice (Mastomys natalensis). Investigations in the 1970s and 1980s pointed to the existence of 3 disease-end...
متن کاملMastomys natalensis and Lassa Fever, West Africa
PCR screening of 1,482 murid rodents from 13 genera caught in 18 different localities of Guinea, West Africa, showed Lassa virus infection only in molecularly typed Mastomys natalensis. Distribution of this rodent and relative abundance compared with M. erythroleucus correlates geographically with Lassa virus seroprevalence in humans.
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ژورنال
عنوان ژورنال: African Journal of Clinical and Experimental Microbiology
سال: 2009
ISSN: 1595-689X
DOI: 10.4314/ajcem.v10i3.43407