Laminar-, event-, and state-dependent population coding in the auditory cortex

State-dependent population coding in primary auditory cortex.

Sensory function is mediated by interactions between external stimuli and intrinsic cortical dynamics that are evident in the modulation of evoked responses by cortical state. A number of recent studies across different modalities have demonstrated that the patterns of activity in neuronal populations can vary strongly between synchronized and desynchronized cortical states, i.e., in the presen...

Binary Coding in Auditory Cortex

Cortical neurons have been reported to use both rate and temporal codes. Here we describe a novel mode in which each neuron generates exactly 0 or 1 action potentials, but not more, in response to a stimulus. We used cell-attached recording, which ensured single-unit isolation, to record responses in rat auditory cortex to brief tone pips. Surprisingly, the majority of neurons exhibited binary ...

Temporal coding in the auditory cortex.

Speech is a complex acoustic signal showing a quasiperiodic structure at several timescales. Integrated neural signals recorded in the cortex also show periodicity at different timescales. In this chapter we outline the neural mechanisms that potentially allow the auditory cortex to segment and encode continuous speech. This chapter focuses on how the human auditory cortex uses the temporal str...

Laminar Structure of Spontaneous and Sensory-Evoked Population Activity in Auditory Cortex

Spontaneous activity plays an important role in the function of neural circuits. Although many similarities between spontaneous and sensory-evoked neocortical activity have been reported, little is known about consistent differences between them. Here, using simultaneously recorded cortical populations and morphologically identified pyramidal cells, we compare the laminar structure of spontaneo...

Population Coding in Laminar Cortical Circuits