Lactobacillus plantarum-derived Extracellular Vesicles Protect Atopic Dermatitis Induced byStaphylococcus aureus-derived Extracellular Vesicles
نویسندگان
چکیده
منابع مشابه
Extracellular vesicles derived from Staphylococcus aureus induce atopic dermatitis-like skin inflammation
BACKGROUND Recently, we found that Staphylococcus aureus produces extracellular vesicles (EV) that contain pathogenic proteins. Although S. aureus infection has been linked with atopic dermatitis (AD), the identities of the causative agents from S. aureus are controversial. We evaluated whether S. aureus-derived EV are causally related to the pathogenesis of AD. METHODS Extracellular vesicles...
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Skin barrier disruption and dermal inflammation are key phenotypes of atopic dermatitis (AD). Staphylococcus aureus secretes extracellular vesicles (EVs), which are involved in AD pathogenesis. Here, we evaluated the role of EVs-associated α-hemolysin derived from S. aureus in AD pathogenesis. α-hemolysin production from S. aureus was detected using western blot analyses. The cytotoxic activity...
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ژورنال
عنوان ژورنال: Allergy, Asthma & Immunology Research
سال: 2018
ISSN: 2092-7355,2092-7363
DOI: 10.4168/aair.2018.10.5.516