Lactate dehydrogenase level as a COVID-19 biomarker

Background: Lactate dehydrogenase (LDH) is an intracellular enzyme found in cells almost all organ systems, which catalyzes the interconversion of pyruvate and lactate, LDH has been proved to be a prognostic factor with high accuracy diseases involving multiple injuries such as acute heart failure (AHF) severe pancreatitis (AP), potential biomarker patients COVID-19. Patients methods: This study included 217 non hospitalized confirmed COVID-19 infection Alexandria, Egypt, these subjects were randomly selected irrespective age group both genders included, Assay procedure manufactory instructions Reagents Chema Diagnostics Italy, FL reagent based on  DGKC recommendations. Results: The percentage relation serum level, present aged from14 years 75 mean was 44.5 ±30.5 who have Covid-19 on real-time reverse transcription-polymerase chain reaction, female gender more frequent (n=119, 54.8%) than Male (n=98, 45.2%). reveals levels 147 (67.7%), significant for diagnosis non-hospitalized (Outpatients under home observation), p-value 0.024 less 0.05. Conclusion Recommendations: Serum level good Outpatients observation increased by 67.7%, many other studies revealed marker COVD-19 infection.