Lactate and hyperlactatemia revisited: an overview
نویسندگان
چکیده
منابع مشابه
Lactate uptake and metabolism by brain during hyperlactatemia and hypoglycemia.
Lactale Uptake and Metabolism by Brain During Hyperlactatemia and Hypoglycemia • Entry into CSF and consumption by brain of blood-borne lactate (La) was quantified in pentobarbital-anesthetized, normocapnic dogs loaded and infused with NaLa and HLa to hold constant, in arterial blood, both the La concentration at about 8 mM (normal = 1 mM) and the pH at 7.4. In four dogs studied hourly over six...
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Blood lactate levels are frequently measured in critically ill patients. Whilst these measurements are known to be accurate, for the correct interpretation of hyperlactataemia, it is essential to have sufficient understanding of anaerobic and aerobic mechanisms of production and clearance. The consistency of the prognostic value emphasizes the place of lactate measurement in the risk-stratifica...
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STUDY OBJECTIVES To determine whether the lungs of patients with fulminant hepatic failure release lactate, and if so, whether this release relates to systemic lactate concentration or acid base status. Another objective was to examine the accuracy of lactate flux calculations in critically ill patients. DESIGN Prospective observational study. SETTING The ICU of a major teaching hospital. ...
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Objective The aim of the study was to describe the prevalence of hyperlactatemia and emphasis on repeated lactate measurements in critically ill patients, and the associated mortality. Materials and methods The study included 70 patients admitted in the Medical Intensive Care Unit at the Clinical Center, University of Sarajevo, in a 6-month period (July - December 2015). The following data we...
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The normal blood lactate level is 0-2 mmol/L, and a value above 3-5 mmol/L is variably used to define hyperlactatemia. In cardiac surgical patients, hyperlactatemia can arise from both hypoxic and non-hypoxic mechanisms. The major non-hypoxic mechanism is likely stress-induced accelerated aerobic metabolism, in which elevated lactate results from a mass effect on the lactate/pyruvate equilibriu...
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ژورنال
عنوان ژورنال: Acta anaesthesiologica Belgica
سال: 2023
ISSN: ['0001-5164']
DOI: https://doi.org/10.56126/74.1.07