Lack of oncogenicity with immunosuppressive therapy

Infection associated with immunosuppressive therapy.

sarcoma' refers to a miscellaneous group of undifferentiated tumours which may represent rather different malignant diseases. An increased incidence of lymphomas has also been observed in three congenital immunological deficiency diseases, namely, ataxia-telangiectasia, the Wiscott-Aldrich and Chediak-Higashi syndromes (Table 4). The evidence that malignant disease is increased in patients who ...

Sideroblastic anemia treated with immunosuppressive therapy.

Improvement Without Immunosuppressive Therapy

We describe a pregnant young woman with branch retinal arteriolar occlusions, encephalopathy, and hearing loss in whom we demonstrated a patent foramen ovale. She improved while receiving anticoagulants and no immunosuppressive therapy. The microangiopathic syndrome of retinopathy, encephalopathy, and deafness may be due to a disturbance of coagulation and/or microembolism. (Stroke 1991;22:933-...

Immunosuppressive drug therapy.

The first successful kidney transplantation between monozygotic identical twins did not require any immunosuppressive drugs. Clinical application of azathioprine and glucocorticosteroids allowed the transfer of organs between genetically disparate donors and recipients. Transplantation is now the standard of care, a life-saving procedure for patients with failed organs. Progress in our understa...

Immunosuppressive therapy in polymyositis.

Immunosuppressive drugs were given to seven patients with polymyositis. The in-vitro activity of peripheral blood lymphocytes had previously been studied in five of these patients with findings suggestive of disturbed immunological processes. Some improvement occurred in five cases, but only in two was the improvement marked and sustained. In this small series of cases, the response to treatmen...