Lack of M30 expression correlates with factors reflecting tumor progression in rectal cancer with preoperative chemoradiotherapy
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چکیده
منابع مشابه
Preoperative Chemoradiotherapy in Elderly Patients with Locally Advanced Rectal Cancer
PURPOSE To evaluate the treatment tolerance and clinical outcomes in patients aged 70 and older with locally advanced rectal carcinoma treated with multimodality approach. METHODS AND MATERIALS We retrospectively analysed 20 consecutive elderly patients, with histologically proven rectal adenocarcinoma, staged T3-4, and/or node-positive tumour, who received chemoradiotherapy and proceeded to ...
متن کاملClinical predictive factors of pathologic tumor response after preoperative chemoradiotherapy in rectal cancer
PURPOSE The aim of this study was to identify clinical predictive factors for tumor response after preoperative chemoradiotherapy (CRT) in rectal cancer. MATERIALS AND METHODS The study involved 51 patients who underwent preoperative CRT followed by surgery between January 2005 and February 2012. Radiotherapy was delivered to the whole pelvis at a dose of 45 Gy in 25 fractions, followed by a ...
متن کاملClinical Significance of Tumor Regression Grade in Rectal Cancer with Preoperative Chemoradiotherapy
PURPOSE Neoadjuvant chemoradiotherapy applied to the locally advanced rectal cancer reduces local recurrence and improves survival. We assessed tumor regression grade (TRG) and its influence on survival in rectal cancer patients treated with chemoradiotherapy followed by surgical resection. METHODS We studied 108 patients that were seen at our hospital between August 2004 and December 2008. P...
متن کاملaccuracy of mri in rectal cancer after preoperative neoadjuvant chemoradiotherapy
methods study on 34 patients diagnosed with rectal adenocarcinoma referred to oncology clinic was conducted. the treatment plan included 4050 cgy radiotherapy and 5fu, xeloda chemotherapy. all patients were assessed with 1/5 t mri 6 to 8 weeks after treatment. t1 and t2 images with sagittal, cronal and axial planes with and without contrast agent were obtained and interpreted by two radiologist...
متن کاملHLA Class I Expression and Its Alteration by Preoperative Hyperthermo-Chemoradiotherapy in Patients with Rectal Cancer
OBJECTIVE Enhancing immunologic responses, including human leukocyte antigen (HLA) class I expression on tumor cells and recognition and elimination of tumor cells by tumor-specific cytotoxic T lymphocyte (CTL), is considered a novel concept of radiotherapy. The present study examined patients who underwent preoperative hyperthermo-chemoradiotherapy (HCRT) for locally advanced rectal cancer to ...
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ژورنال
عنوان ژورنال: Molecular and Clinical Oncology
سال: 2013
ISSN: 2049-9450,2049-9469
DOI: 10.3892/mco.2013.189