Lack of evidence for an association between UCHL1 S18Y and Parkinson’s disease

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UCHL1 S18Y variant is a risk factor for Parkinson’s disease in Japan

BACKGROUND A recent meta-analysis on the UCHL1 S18Y variant and Parkinson's disease (PD) showed a significant inverse association between the Y allele and PD; the individual studies included in that meta-analysis, however, have produced conflicting results. We examined the relationship between UCHL1 S18Y single nucleotide polymorphism (SNP) and sporadic PD in Japan. METHODS Included were 229 ...

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ژورنال

عنوان ژورنال: European Journal of Neurology

سال: 2007

ISSN: 1351-5101

DOI: 10.1111/j.1468-1331.2007.02012.x