Laboratory parameters in centenarians of Italian ancestry

Von Willebrand factor in Italian centenarians.

BACKGROUND AND OBJECTIVES Subjects with blood type O have lower concentration of von Willebrand factor (VWF) than those with type A, B or AB. Since we recently observed that laboratory signs of marked hypercoagulability are compatible with health and longevity in Italian centenarians, we determined VWF and blood groups in healthy centenarians to see whether levels of this marker of endothelial ...

The role of laboratory parameters in COVID-19 diagnosis

Distribution of Laboratory Parameters in Trauma Population

Background Biochemical laboratory investigations help plan optimum management and communication in short- as well as long-term outcome to trauma victims. Objective To assess the status of real-time values of biochemical laboratory investigations of different trauma patients and their association with overall mortality. Materials and Methods Data based on prospective, observational registry ...

Adoption of TSH Reflex algorithm in an Italian clinical laboratory.

BACKGROUND TSH Reflex is an automated diagnostic algorithm which follows the rule "If ... then", in which the initial determination of TSH is followed by the determination of fT4, and possibly of fT3, if TSH is not within the reference limits. The aim of our study was to evaluate the results of the introduction and implementation of the test "TSH Reflex", which started in late 2013 in the hospi...

Prevalence of C282Y and E168X HFE mutations in an Italian population of Northern European ancestry.

BACKGROUND AND OBJECTIVES In Italy, the prevalence of C282Y is lower than in Northern European countries. We hypothesized a higher prevalence of C282Y in Northern than in Southern Italian populations. We previously identified a nonsense mutation (E168X) in hemochromatosis probands originating from a region in the north-west of Italy. We aimed to define the prevalence of C282Y and E168X in that ...