Laboratory Markers Indicating Gastrointestinal Involvement of Henoch-Schönlein Purpura in Children

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Laboratory Markers Indicating Gastrointestinal Involvement of Henoch-Schönlein Purpura in Children

PURPOSE To determine clinically useful biochemical markers reflecting disease activity and/or gastrointestinal (GI) tract involvement in Henoch-Schönlein purpura (HSP). METHODS A total of 185 children with HSP and 130 controls were included. Laboratory data indicating inflammation, standard coagulation, and activated coagulation were analyzed for the HSP patients, including measurements of th...

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Henoch-Schönlein purpura in children.

Henoch-Schönlein purpura is the most common systemic vasculitis of childhood. In the majority of children, the outcome of Henoch-Schönlein purpura is excellent with spontaneous resolution of symptoms and signs. However, a small subset of patients will develop long-term sequelae in the form of chronic kidney disease. While the clinical presentation and diagnosis of Henoch-Schönlein purpura is st...

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Gastrointestinal manifestations of Henoch-Schönlein purpura.

We report a case of the intestinal lesion in Henoch-Schönlein purpura, presented with an acute abdomen in a 4 year old boy. Five days after sudden colicky abdominal pain, skin purpura and painful joint swelling developed. These manifestations were associated with abdominal distension, hematemesis, hematochezia and hematuria. Exploratory laparotomy revealed a marked bowel distension with edema a...

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Henoch-Schönlein purpura nephritis.

Henoch-Schönlein purpura (HSP) is a systemic vasculitic disorder first reported by Heberden in 1806. The association of purpura and joint pain was described by Schönlein in 1837, who termed it “peliosis rheumatica.” Henoch added a description of four children with skin lesions associated with colicky abdominal pain, gastrointestinal hemorrhage, and joint pain in 1874, and in 1899 pointed out th...

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Henoch-Schönlein purpura.

Henoch-Schönlein purpura commonly occurs in children at about age five. There is no known etiologic agent. The illness is characterized by skin rash, joint pain, edema and gastrointestinal symptoms. Laboratory tests are not diagnostic. Although there is no specific treatment, steroids may help prevent serious gastrointestinal complications. Prognosis is good, except for those patients with adva...

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ژورنال

عنوان ژورنال: Pediatric Gastroenterology, Hepatology & Nutrition

سال: 2015

ISSN: 2234-8646,2234-8840

DOI: 10.5223/pghn.2015.18.1.39