KUZEY AFRİKA'DA ŞAHKLI BİR MÜFESSİR : YAHYA İBN SELLAM (742-815)

Npgrj_ni_1621 733..742

The cellular basis of immunological memory remains a controversial issue. Here we show that basophils bound large amounts of intact antigens on their surface and were the main source of interleukins 6 and 4 in the spleen and bone marrow after restimulation with a soluble antigen. Depletion of basophils resulted in a much lower humoral memory response and greater susceptibility of immunized mice...

Op-brai120288 815..827

1 Département de Psychologie, Université de Montréal, Montreal, Quebec, Canada 2 Centre de recherche de l’Institut universitaire de gériatrie de Montréal (CRIUGM), Montreal, Quebec, Canada 3 Department of Psychology, Columbia University, Montreal, Quebec, Canada 4 Department of Anaesthesiology, Harvard Medical School, Boston, MA, USA 5 Department of Stomatology, Faculty of Dentistry, Université...

Dev119016 732..742

Second heart field (SHF) progenitors exhibit continued proliferation and delayed differentiation, which are modulated by FGF4/8/10, BMP and canonical Wnt/β-catenin signaling. PTEN-Akt signaling regulates the stem cell/progenitor cell homeostasis in several systems, such as hematopoietic stem cells, intestinal stem cells and neural progenitor cells. To address whether PTEN-Akt signaling is invol...

Dmm019935 805..815

The cells of the intestinal epithelium provide a selectively permeable barrier between the external environment and internal tissues. The integrity of this barrier is maintained by tight junctions, specialised cell-cell contacts that permit the absorption of water and nutrients while excluding microbes, toxins and dietary antigens. Impairment of intestinal barrier function contributes to multip...

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