Kinetochores feel the pull
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چکیده
منابع مشابه
Kinetochores feel the pull
S uzuki et al. (1) take a close look at how kinetochores change shape when spindle microtubules tug on them. They fi nd that only part of the kinetochore stretches and identify a protein that might confer this ability. Kinetochores, which hook the fi bers of the mitotic spindle to chromosomes, are more than passive fasteners. Fashioned from more than 100 proteins, the structures are dynamic and...
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Not to be confused with1⁄4 centrosomes. But it’s OK to confuse them with centromeres. The centromere is the chromosomal domain where the kinetochore is assembled. Genetically speaking, the centromere is the locus necessary to segregate chromosomes. In many species, the centromere is also defined cytologically as the primary constriction visible on condensed chromosomes (the intersection point o...
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ژورنال
عنوان ژورنال: Journal of Cell Biology
سال: 2011
ISSN: 1540-8140,0021-9525
DOI: 10.1083/jcb.1931if