Kinetic and Spectroscopic Studies of Bicupin Oxalate Oxidase and Putative Active Site Mutants
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چکیده
منابع مشابه
Kinetic and Spectroscopic Studies of Bicupin Oxalate Oxidase and Putative Active Site Mutants
Ceriporiopsis subvermispora oxalate oxidase (CsOxOx) is the first bicupin enzyme identified that catalyzes manganese-dependent oxidation of oxalate. In previous work, we have shown that the dominant contribution to catalysis comes from the monoprotonated form of oxalate binding to a form of the enzyme in which an active site carboxylic acid residue must be unprotonated. CsOxOx shares greatest s...
متن کاملHydrogen peroxide inhibition of bicupin oxalate oxidase
Oxalate oxidase is a manganese containing enzyme that catalyzes the oxidation of oxalate to carbon dioxide in a reaction that is coupled with the reduction of oxygen to hydrogen peroxide. Oxalate oxidase from Ceriporiopsis subvermispora (CsOxOx) is the first fungal and bicupin enzyme identified that catalyzes this reaction. Potential applications of oxalate oxidase for use in pancreatic cancer ...
متن کاملHydrogen Peroxide Inhibition and Inactivation of Bicupin Oxalate Oxidase
................................................................................................................ iii TABLE OF CONTENTS .............................................................................................. iv LIST OF ABBREVIATIONS ........................................................................................ x CHAPTER 1: INTRODUCTION ..............................
متن کاملpostnatal studies of bats (pipistrellus kuhlii and miniopterus schreibersii) & histomorphology and histochemistry studies of organs and diseases of (neurergus microspilotus and n. kaiseri)
1. to determine whether difference in birth body mass influenced growth performance in pipistrellus kuhlii we studied a total of 12 captive-born neonates. bats were assigned to two body mass groups: light birth body mass (lbw: 0.89 ± 0.05, n=8) and heavy birth body mass (hbw: 1.35 ± 0.08, n=4). heavier body mass at birth was associated with rapid postnatal growth (body mass and forearm length) ...
Structure and function studies of oxalate oxidase.
Oxalate oxidase (E.C. 1.2.3.4) catalyses the conversion of oxalate and dioxygen to carbon dioxide and hydrogen peroxide (for reviews see [ 1-31). Oxalate oxidase activity has been detected in a number of organisms but the best biochemically characterised enzymes are from barley and wheat. The plant enzyme is isolated as a glycosylated homopentamer which is remarkably resistant to heat, SDS and ...
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ژورنال
عنوان ژورنال: The FASEB Journal
سال: 2013
ISSN: 0892-6638,1530-6860
DOI: 10.1096/fasebj.27.1_supplement.789.9