Kidney microRNA-21 Expression and Kidney Function in IgA Nephropathy
نویسندگان
چکیده
منابع مشابه
Histological changes of kidney in diabetic nephropathy
Diabetes mellitus is the most common cause of chronic renal disorders and end-stage kidney disease in developed countries. It is the major cause of dialysis and transplantation. Failure in renal function causes wide disorders in the body. Diabetes results in wide range of alterations in the renal tissue. It is believed that early histological changes in diabetic nephropathy are detectabl...
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IgA nephropathy (IgAN) is the most common GN in the world. Prevalence of IgAN is extremely high, noted in 30%– 40% of renal biopsies in Asian countries and South Europe. In Japan, the Renal Biopsy Registry compiles information from .1500 cases a year, among which the most frequent pathologic diagnosis is IgAN at 30%. Glomerular IgA deposition is observed in 16% of zero-hour biopsies, and IgA ne...
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Glomerulonephritis (GN) is the main cause of chronic kidney disease (CKD) in patients on renal replacement therapy, with IgA nephropathy (IgAN) being the most frequent single diagnosis. Patients with reduced kidney function and/or proteinuria have an increased risk of premature cardiovascular disease (CVD). Based on the assumption that progression of atherosclerosis and glomerulosclerosis share...
متن کاملKidney injury molecule-1 expression in IgA nephropathy and its correlation with hypoxia and tubulointerstitial inflammation.
Tubulointerstitial injury plays an important role in the development and progression of chronic kidney disease (CKD). Kidney injury molecule (KIM)-1 is induced in damaged proximal tubules in both acute renal injury and CKD. However, the dynamics of KIM-1 in CKD and effects of KIM-1 expression on disease progression are unknown. Here, we aimed to determine the associations between tubular KIM-1 ...
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The intrarenal renin-angiotensin system plays a crucial role in the regulation of renal circulation and sodium reabsorption through the activation of vascular, glomerular, and tubular angiotensin II type 1 (AT(1)) receptor signaling. We previously cloned a molecule that specifically interacted with the murine AT(1) receptor to inhibit AT(1) receptor signaling, which we named ATRAP (for AT(1) re...
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ژورنال
عنوان ژورنال: Kidney Medicine
سال: 2021
ISSN: 2590-0595
DOI: 10.1016/j.xkme.2020.11.009