KETOROLAC ENTERIC MATRIX PELLETS PRODUCED BY EXTRUSION / SPHERONIZATION
نویسندگان
چکیده
منابع مشابه
Development and evaluation of omeprazole pellets fabricated by sieving-spheronization and extrusion - spheronization process.
Pelletized dosage forms can be prepared by different methods which, in general, are time consuming and labor intensive. The current study was carried out to investigate the feasibility of preparing the spherical pellets of omeprazole by sieving-spheronization. An optimized formulation was also prepared by extrusion-spheronization process to compare the physical parameters between these two meth...
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In this study, five microcrystalline cellulose (MCC) grades were physically characterized and their extrusion-spheronization behaviours were characterized in terms of water requirements and pellet shape profiles. It was found that the MCC grades differed significantly in the physical properties investigated. Physical properties of MCC were found to influence the water requirement for extrusion-...
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Background and objectives: Carvacrol is one of the main pharmacologically active components of Thymus vulgaris essential oil which has shown several therapeutic effects. There are few works regarding the formulation of essential oils as oral solid dosage forms due to their liquid nature, stability and technical problems. The aim of this study was to combine the solid-d...
متن کاملCompression and evaluation of extended release matrix pellets prepared by the extrusion/spheronization process into disintegrating tablets
In this study, a novel approach for compression of matrix pellets into disintegrating tablets has been studied in an attempt to overcome the issues pertaining to rupture of polymer coat during compression of reservoirtype pellets. Extended release matrix pellets were prepared by the extrusion/spheronization technique using commercially available aqueous dispersions of ethyl cellulose, acrylic p...
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ژورنال
عنوان ژورنال: Bulletin of Pharmaceutical Sciences. Assiut
سال: 2010
ISSN: 1110-0052
DOI: 10.21608/bfsa.2010.147023