Kernel methods for predicting protein-protein interactions

نویسندگان
چکیده

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Kernel methods for predicting protein-protein interactions

MOTIVATION Despite advances in high-throughput methods for discovering protein-protein interactions, the interaction networks of even well-studied model organisms are sketchy at best, highlighting the continued need for computational methods to help direct experimentalists in the search for novel interactions. RESULTS We present a kernel method for predicting protein-protein interactions usin...

متن کامل

Computational methods for predicting protein-protein interactions.

Protein-protein interactions (PPIs) play a critical role in many cellular functions. A number of experimental techniques have been applied to discover PPIs; however, these techniques are expensive in terms of time, money, and expertise. There are also large discrepancies between the PPI data collected by the same or different techniques in the same organism. We therefore turn to computational t...

متن کامل

Predicting Functional Protein-Protein Interactions Based on Computational Methods

Protein-protein interactions play a crucial role in the cellular process. In recent years, yet new experimental techniques have been developed to discover the protein-protein interaction networks, the accuracy and coverage has still proven to be limited. Computational approaches come into being essential both to assist in the design and validation of experimental studies and for the prediction ...

متن کامل

Optical methods for measuring protein-protein interactions.

The hepatopancreas protein, therefore, probably represents the membranous proton channel of the vacuolar ATPase and electron microscopy has given us the clearest impression yet of its organization; an organization clearly consistent with the functional characteristics of the chloroplast ATPase-CF,, complex [22]. It is hoped that techniques such as electron diffraction may improve the structural...

متن کامل

Methods for detecting protein–protein interactions

The increasing rate at which complete genome sequences become available necessitates rapid and robust methods for investigating the functions of their encoded proteins. Efforts have been made to study protein function by systematically screening large sets of proteins using the two-hybrid method. Analyses of the complete proteomes of baceriophage T7, the mammalian viruses hepatitis C and vaccin...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Bioinformatics

سال: 2005

ISSN: 1367-4803,1460-2059

DOI: 10.1093/bioinformatics/bti1016