Keeping RNA away from DNA

Keeping RNA away from DNA

JCB • VOLUME 170 • NUMBER 6 • 2005 862 Keeping RNA away from DNA ewly transcribed RNA represents a threat to genomic stability, say Xialu Li and James Manley (Columbia University, New York, NY). They find that, in metazoan cells, the threat is neutralized by a splicing factor that coats RNA as it it emerges from RNA polymerase. The danger arises because nascent RNA can anneal to the template DN...

Keeping the Kell away from immunity.

Why are students keeping away from wards?

Keeping the Monkeys Away from the Typewriters: an Anthropologist's View of the Consumer Behavior Odyssey

In this essay, the Consumer Behavior Odyssey is subjected to a premature personal evaluation. The project is viewed in both its scientific and mythopoeic aspects, as a significant pilot with potentially profound long term consequences.

DNA Repair: Keeping It Together

A protein scaffold has been identified that holds a chromosome together in the event of a DNA double-strand break. This scaffold is dependent on Rad52 and the Rad50-Mre11-Xrs2 complex and withstands the pulling forces of the mitotic spindle during DNA damage checkpoint arrest.