Kasabach-Merritt syndrome with large cutaneous vascular tumors

Cutaneous angiosarcoma associated with the Kasabach-Merritt syndrome.

Dear Editor, Angiosarcoma is a rare tumour commonly affecting elderly men, usually occurring on the head and neck region.1 The tumour usually presents as ecchymosis-like plaques, and less commonly with haemorrhage, oedema, ulceration and recurrent facial angioedema. Kasabach-Merritt syndrome (KMS) may occur in association with a vascular tumour and is characterised by consumption of platelets a...

Kasabach-Merritt syndrome.

Hemangiomas of infancy are usually congenital lesions. Occasionally they are associated with microangiopatbic bemolytic anaemia, thrombocytopenia, and a consumptive coagulopathy. This is most often associated with cavernous hemangiomas. Thrombocytopenia associated with giant cavernous hemangiomas was first noted by Kasabach and Merritt in 1940. As the primary mechanism of platelet destruction i...

Haemangioma with thrombocytopenia (Kasabach-Merritt syndrome).

We describe two patients with haemangioma with thrombocytopenia (Kasabach-Merritt syndrome). Both were treated with corticosteroids without notable improvement. The first patient responded satisfactorily to radiotherapy, whereas the second showed a slow spontaneous resolution.

About the Treatment of Kasabach-Merritt Syndrome

94 To the Editor, Dr. Emre and colleagues briefly reported on a 24-year-old female with Kasabach-Merritt syndrome in the most recent issue of this journal [1]. Three units of fresh frozen plasma were administrated within 3 days to the patient for the correction of severe hypofibrinogenemia despite a very high D-dimer level (5000 ng/mL), both of which reflected consumption coagulopathy, as state...

Kaposiform Hemangioendothelioma in a Newborn with Kasabach-Merritt Syndrome