Juxtacortical Lesions and Cortical Thinning in Multiple Sclerosis
نویسندگان
چکیده
منابع مشابه
Juxtacortical Lesions and Cortical Thinning in Multiple Sclerosis.
BACKGROUND AND PURPOSE The role of juxtacortical lesions in brain volume loss in multiple sclerosis has not been fully clarified. The aim of this study was to explore the role of juxtacortical lesions on cortical atrophy and to investigate whether the presence of juxtacortical lesions is related to local cortical thinning in the early stages of MS. MATERIALS AND METHODS A total of 131 patient...
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OBJECTIVE It has been suggested recently that cortical pathology in multiple sclerosis (MS) may, at least partly, be caused by factors in cerebrospinal fluid (CSF). We thus hypothesized that MS-related tissue changes in compartments close to the CSF, such as periventricular lesions, might correlate with cortical pathology. METHODS We investigated a cohort of 160 patients, comprising 91 with a...
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BACKGROUND Autopsy studies showed cortical and juxtacortical multiple sclerosis (MS) plaques. Fluid-attenuated inversion recovery (FLAIR) is an advanced magnetic resonance imaging sequence that reveals tissue T2 prolongation with cerebrospinal fluid suppression, allowing detection of superficial brain lesions. OBJECTIVES To assess FLAIR, T1-weighted, and T2-weighted images for detecting lesio...
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Although previous studies have shown that the lesions of multiple sclerosis may involve the cerebral cortex, there is little published research on the prevalence and distribution of such lesions. Using neuropathological techniques and MRI, a series of studies has been undertaken in order to assess this, in particular to identify their relationship to cortical veins. A serial MRI study showed th...
متن کاملJuxtacortical Lesions in Multiple Sclerosis: Assessment of Gray Matter Involvement Using Phase Difference-enhanced Imaging (PADRE)
PURPOSE In multiple sclerosis (MS), a juxtacortical lesion at the border between the gray matter (GM) and subcortical white matter (WM) may often involve the GM. A recently developed, phase-weighted magnetic resonance imaging (MRI) technique "phase difference enhanced imaging (PADRE)" can delineate the GM and WM clearly due to the difference in myelin concentration. We evaluated whether PADRE i...
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ژورنال
عنوان ژورنال: American Journal of Neuroradiology
سال: 2015
ISSN: 0195-6108,1936-959X
DOI: 10.3174/ajnr.a4485