Josef Brudzinski (1874-1917)

Josef Brudzinski and Vladimir Mikhailovich Kernig: signs for diagnosing meningitis.

Inflammation of the meninges, or meningitis, is a serious neurological insult that involves the membranes (dura, pia and arachnoid matter) covering the brain and spinal cord. Meningitis may be caused by any of a host of infectious and noninfectious agents including bacteria, viruses, fungi, parasites, drugs, autoimmune disorders, or malignancy which considerably influences morbidity and mortali...

Josef Richter

The signs of Kernig and Brudzinski.

Dmd052597 1867..1874

The primary objective of this study was to determine the in vivo absorption properties of valacyclovir, including the potential for saturable proton-coupled oligopeptide transporter 1 (PepT1)-mediated intestinal uptake, after escalating oral doses of prodrug within the clinical dose range. A secondary aim was to characterize the role of PepT1 on the tissue distribution of its active metabolite,...

Arguments in English Josef

Despite the idiosyncratic properties of null-complement phenomena observed by Fillmore (1986), Lambrecht and Lemoine (2005), and others, many researchers have pursued large-scope, single-factor explanations of the distributional and interpretive restrictions on null complements—in particular, explanations based on Aktionsart (Rappaport Hovav and Levin 1998) and selectional restrictions (Resnik ...