Jak3 activation in human lymphocyte precursor cells
نویسندگان
چکیده
منابع مشابه
Radioadaptive Response in Human Lymphocyte Cells
The adaptive response (AR) is a phenomenon by which cells exposure to sublethal doses of DNA-damaging agents (non-mutagenic dose of chemical or radiation), known as conditioning treatment (CT), leads to increased resistance to a subsequent exposure to a higher dose of the same or other agents, known as challenge treatment (CR). The adaptive response (AR) induced by radiation in human lymphocyte...
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Jak3, a member of the Janus kinase family of cytoplasmic tyrosine kinases, is expressed at low levels in immature hematopoietic cells and its expression is dramatically up-regulated during the terminal differentiation of these cells. To better understand the role of Jak3 in myeloid cell development, we have investigated the role of Jak3 in myeloid cell differentiation using the 32Dcl3 cell syst...
متن کاملradioadaptive response in human lymphocyte cells
the adaptive response (ar) is a phenomenon by which cells exposure to sublethal doses of dna-damaging agents (non-mutagenic dose of chemical or radiation), known as conditioning treatment (ct), leads to increased resistance to a subsequent exposure to a higher dose of the same or other agents, known as challenge treatment (cr). the adaptive response (ar) induced by radiation in human lymphocyte...
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Background & objectives: Nuclear Factor kappa B (NF-κB), a master switch transcription factor, plays a critical role in the progression and development of hyperglycemia-induced microangiopathy. Hyperglycemia activates NF-κB, and subsequently increases pro-inflammatory cytokines such as TNF-α, IL-6 and IL-1β leading to development of inflammation. Some new studies have revealed the involvement o...
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From the *Leuhaemia Research Fund Centre, Institute of Cancer Research, London SW3 6JB; the eMRC Radiobiology Unit, Didcot 0XI10Rs United Kingdom; the $Oncogene and Tumor Suppressor Gene Program, La Jolla Cancer Research Foundation, La Jolla, California 92037; and the IIDepartment of Medicine, Microbiology and Immunology, Howard Hughes Medical Institute, Washington University School of Medicine...
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ژورنال
عنوان ژورنال: Clinical & Experimental Immunology
سال: 1997
ISSN: 0009-9104
DOI: 10.1046/j.1365-2249.1997.4001304.x