منابع مشابه
Jacobsen syndrome
Jacobsen syndrome is a MCA/MR contiguous gene syndrome caused by partial deletion of the long arm of chromosome 11. To date, over 200 cases have been reported. The prevalence has been estimated at 1/100,000 births, with a female/male ratio 2:1. The most common clinical features include pre- and postnatal physical growth retardation, psychomotor retardation, and characteristic facial dysmorphism...
متن کاملOcular findings in Jacobsen syndrome.
PURPOSE To discuss the ophthalmic findings and their clinical significance in 10 new cases of Jacobsen syndrome (mental retardation, craniofacial anomalies, congenital heart defects, and blood dyscrasias) and to review the ophthalmic findings in all previously reported cases in the literature. METHODS Ten new cases of Jacobsen syndrome were collected and studied prospectively for detection of...
متن کاملJacob " Evolution and Tinkering " ( 1977 ) , by Francois Jacob
In his essay "Evolution and Tinkering," published in Science in 1977, François Jacob argues that a common analogy between the process of evolution [4] by natural selection [5] and the methods of engineering is problematic. Instead, he proposes to describe the process of evolution [4] with the concept of bricolage (tinkering). In this essay, Jacob does not deny the importance of the mechanism of...
متن کاملNuchal thickening in Jacobsen syndrome.
A routine detailed ultrasound examination performed at 20 weeks' gestation demonstrated the presence of nuchal thickening as an apparently isolated finding. The concentration of maternal alpha-fetoprotein was normal and the risk of Down's syndrome was 1 in 6800. Amniocentesis was performed and chromosome analysis showed the karyotype 46,XY, del(11)(q23) found in Jacobsen syndrome. Fetal autopsy...
متن کاملJacob Ross
How is what an agent ought to do related to what an agent ought to prefer that she does? More precisely, suppose we know what an agent’s preference ordering ought to be over the outcomes of performing the various courses of action open to her. Can we infer from this information how she ought to act, and if so, how can we infer it? One view (which, for convenience, I will call ‘actualism’) is th...
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ژورنال
عنوان ژورنال: ICES Journal of Marine Science
سال: 1948
ISSN: 1054-3139,1095-9289
DOI: 10.1093/icesjms/15.2.154