Itaconic acid mediates crosstalk between macrophage metabolism and peritoneal tumors
نویسندگان
چکیده
منابع مشابه
Noninductive metabolism of itaconic acid by Pseudomonas and Salmonella species.
Martin, William R. (University of Chicago, Chicago, Ill.), Frank Frigan, and Edna H. Bergman. Noninductive metabolism of itaconic acid by Pseudomonas and Salmonella species. J. Bacteriol. 82:905-908. 1961-Ten molds, three yeasts, and 44 bacteria were screened for the noninductive metabolism of itaconic acid by growing in complete media containing traces of C(14)-labeled itaconic acid. Several S...
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The natural occurrence of a great variety of methyl and methylene-substituted dicarboxylic acids has prompted an investigation of the metabolism of some of these compounds by animal tissues. Guinea pig liver mitochondria did not catalyze measurably the oxidation of citraconate, dl-citramalate, P-methyl malate, itamalate, or paraconate. Itaconic acid’ was oxidized as rapidly as most members of t...
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The morphology of filamentous fungi closely correlates with the productivity in submerged culture. Using itaconic acid (IA) production by Aspergillus terreus as a research model, the quantitative relationship between the growth form of A. terreus and IA production was investigated. IA fermentation was scaled up from shake flasks to a 7 L stirred tank bioreactor based on the quantitative relatio...
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Many aspects of physiology and behavior in organisms from bacteria to man are subjected to circadian regulation. Indeed, the major function of the circadian clock consists in the adaptation of physiology to daily environmental change and the accompanying stresses such as exposition to UV-light and food-contained toxic compounds. In this way, most aspects of xenobiotic detoxification are subject...
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Oxygen delivery is essential to sustain all vital functions. Vertebrate organisms have, therefore, evolved sophisticated and tightly regulated mechanisms to ensure continuous red cell synthesis. Chronic or acute blood losses trigger multiple feedback mechanisms aimed at increasing erythropoiesis and minimizing the damage associated with profound anemia and hypoxia. Iron is an element of paramou...
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ژورنال
عنوان ژورنال: Journal of Clinical Investigation
سال: 2018
ISSN: 0021-9738,1558-8238
DOI: 10.1172/jci99169