It takes more than one—Is a single UGT polymorphism enough to bother detoxification?

Checkpoints: It takes more than time to heal some wounds

The S-phase DNA damage checkpoint seems to provide a twist on the checkpoint theme. Instead of delaying replication and allowing repair as a consequence, it may activate repair and delay replication as a consequence.

Trust in Vaccines: Why It Takes More than Good Faith

This Vaccines issue on "Confidence in Vaccines" provides sound evidence through multiple perspectives of life-saving impacts when vaccination programs are effectively implemented in a population. Yet there remain challenges to achieving this impact, including scientific, medical, manufacturing, policy-related and logistical issues. Additionally, socio-cultural, religious and political agendas c...

It takes more than breadcrumbs to learn generic skills: Collaborating to improve information literacy

The effective teaching and learning of generic skills is becoming an important component of undergraduate education with the introduction of graduate attribute programmes in some Australian universities. Research shows that contextualised learning of these skills is important, but is a discipline-specific context sufficient to ensure student success in acquiring these skills? This paper studies...

Improving clinical quality indicators through electronic health records: it takes more than just a reminder.

Cervical spine clearance in the obtunded patient: it takes more than a simple CT.

A basic assumption of caring for multi-injured patients is that all patients are suspected of having a cervical spine injury until proven otherwise. It is known that 2% to 4% of all blunt trauma injury patients have a cervical spine injury. Missed or delayed diagnosis of cervical spine injury occurs in 4% to 8% of patients of whom 70% have altered levels of consciousness. When these missed diag...