Isotope pattern deconvolution for peptide mass spectrometry by non-negative least squares/least absolute deviation template matching
نویسندگان
چکیده
منابع مشابه
Analysis of least absolute deviation
The least absolute deviation or L1 method is a widely known alternative to the classical least squares or L2 method for statistical analysis of linear regression models. Instead of minimizing the sum of squared errors, it minimizes the sum of absolute values of errors. Despite its long history and many ground-breaking works (cf. Portnoy and Koenker (1997) and references therein), the former has...
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The linear absolute shrinkage and selection operator(Lasso) method improves the low prediction accuracy and poor interpretation of the ordinary least squares(OLS) estimate through the use of L1 regularization on the regression coefficients. However, the Lasso is not robust to outliers, because the Lasso method minimizes the sum of squared residual errors. Even though the least absolute deviatio...
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Human breast milk can be considered as “ideal” food for the correct development of newborn babies and, for those that are not breast-fed, formula milk has to be used instead. Ideally, the composition of such formula milk preparations should closely resemble that of maternal human milk. Considerable differences between both in the total content of trace elements such as Fe, Cu, Se, Zn, and I and...
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It is well known that the least absolute deviation (LAD) estimators are more robust than the least squares estimators particularly in presence of heavy tail errors. We consider the LAD estimators of the unknown parameters of one dimensional chirp signal model under independent and identically distributed error structure. The proposed estimators are strongly consistent and it is observed that th...
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We propose a least absolute deviation model for obtaining OWA operator weights: Minimize ∑i=n−1 i=1 |wi − wi−1| subject to orness(W ) = ∑n i=1 n−i n−1wi = α, 0 ≤ α ≤ 1, w1 + · · ·+ wn = 1, 0 ≤ wi, i = 1, · · · , n. Recently, the extended minimax disparity problem was proved by Hong [Fuzzy Sets and Systems, 168 (2011) 35-46]. In this paper, we investigated the equivalence of the solutions for th...
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ژورنال
عنوان ژورنال: BMC Bioinformatics
سال: 2012
ISSN: 1471-2105
DOI: 10.1186/1471-2105-13-291