Isolation, Structural Elucidation, and Cytotoxicity of Three New ent-Kaurane Diterpenoids from Isodon japonica var. glaucocalyx
نویسندگان
چکیده
منابع مشابه
Isolation, structural elucidation, and cytotoxicity of three new ent-kaurane diterpenoids from Isodon japonica var. glaucocalyx.
Three new ENT-kaurane diterpenoids, glaucocalyxin H ( 1), glaucocalyxin I ( 2), and glaucocalyxin J ( 3), together with four known diterpenoids ( 4- 7), were isolated from the leaves of Isodon japonica Hara var. glaucocalyx. Their structures were elucidated by spectroscopic analysis, and the structures of compounds 2 and 3 were further confirmed by X-ray crystallographic analysis. Compounds 1, ...
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The title compound, 14β-acet-oxy-7α-hydr-oxy-ent-kaur-16-ene-3,15-dione or glaucocalyxin B, C(22)H(30)O(5), a natural ent-kaurane diterpenoid, is composed of four rings with the expected cis and trans ring junctions. In the crystal structure, there are two mol-ecules in the asymmetric unit related by a noncrystallographic twofold screw axis, and ring A is disordered [ratio occupancies 0.829 (19...
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ژورنال
عنوان ژورنال: Planta Medica
سال: 2013
ISSN: 0032-0943,1439-0221
DOI: 10.1055/s-0033-1350998