Isolation of mutants blocked in calicheamicin biosynthesis
نویسندگان
چکیده
منابع مشابه
Isolation of mutants blocked in calicheamicin biosynthesis.
Blocked mutants of Micromonospora echinospora defective in the production of the potent antitumor agent calicheamicin are described. Analysis of intermediates produced by blocked mutants indicates a branched biosynthetic pathway. Mutants that produced some, but not all, calicheamicin forms are also described.
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ژورنال
عنوان ژورنال: Journal of Bacteriology
سال: 1991
ISSN: 0021-9193,1098-5530
DOI: 10.1128/jb.173.23.7716-7718.1991