Isolation and cytotoxicity of deoxyluteoskyrin (DLs) from Penicillium islandicum
نویسندگان
چکیده
منابع مشابه
Production of luteoskyrin and isolation of a new metabolite, pibasterol, from Penicillium islandicum Sopp.
Production of luteoskyrin, a hepatotoxin synthesized by Penicillium islandicum Sopp., was studied with various fermentation methods. Best results were obtained in static fermentations on glutinous rice at 30 degrees C. The isolated yield of pure luteoskyrin was approximately 400 mg per kg of rice. Also produced were skyrin, islandicin, iridoskyrin, rubroskyrin, chrysophanol, mannitol, and eryth...
متن کاملProduction of luteoskyrin, a hepatotoxic pigment, by Penicillium islandicum Sopp.
Various factors affecting the yields of luteoskyrin, a hepatotoxic mycotoxin, and related pigments in the liquid medium were studied. Maximal yields of luteoskyrin (0.13% by isolation) and of other pigments were attained in the late phase of the cultivation. The yield of the pigment was increased by supplying malt extract, malonic acid, glutamic acid, or asparagine. A useful material for prepar...
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National Peanut Research Laboratory, U.S. Department ofAgriculture, Dawson, Georgia 31742'; National Institute ofEnvironmental Health Sciences, Research Triangle Park, North Carolina 277092; Plant Pathology Department, University of Georgia, Coastal Plain Experiment Station, Tifton, Georgia 317933; Richard B. Russell Agricultural Research Center, U.S. Department ofAgriculture, Athens, Georgia 3...
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کاتالیست یک سنتز جدید برای تیواترها توصیف شده است. واکنش الکل ها با آریل، هتروآریل و آلکیل تیو ل ها درحضور 1،3،5- تری آزو- 2،4،6- تری فسفرین-2،2،4،4،6،6 هگزاکلراید ((tapc به عنوان یک کاتالیست موُثر، بازده های خوب تا عالی از تیواترها را حاصل می کند. علاوه براین، واکنش تحت شرایط بدون فلز و بدون حلال پیش می رود، بنابراین یک مکمل جالب برای روش های شناخته شده سنتز تیواترها ارائه می دهد. یک مکانیسم ا...
15 صفحه اولIsolation and partial characterization of a mycotoxin from Penicillium roqueforti.
Extracts of pure cultures of Penicillium roqueforti isolated from toxic feed samples and of P. roqueforti NRRL 849 were lethal to rats by either intraperitoneal or oral administration. Purification studies guided by this test led to the isolation of a major toxin which showed intraperitoneal and oral median lethal dose values in weanling rats of 11 and 115 mg/kg, respectively. Partial character...
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ژورنال
عنوان ژورنال: Mycotoxins
سال: 1985
ISSN: 0285-1466,1881-0128
DOI: 10.2520/myco1975.1985.22_21