Islet xenotransplantation: how sweet it is.
نویسندگان
چکیده
منابع مشابه
Duarte galactosemia: how sweet is it?
The pathologic consequences of various inborn errors of metabolism in the conversion of dietary and endogenously produced galactose through the Leloir pathway have recently been reviewed (1, 2 ). In this issue of the Journal, Ficicioglu and colleagues (3 ) report that children (ages 1– 6 years) who have Duarte galactosemia (DG), a variant form of galactosemia, and are on a standard diet have ty...
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Abstract Background and Objectives Transfusion of platelet has become one of the main treatments for thrombocytopenic patients to reduce the severity and frequency of bleeding consequences. Failure to attain the desired level of platelets in a patient following platelet transfusion is defined as platelet refractoriness. The purpose of present paper is to review and study the mechanisms involve...
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Type 1 diabetes (T1D) is a major health problem throughout the world. In the U.S., it is estimated that about 1.5 million people suffer from T1D. Even when well controlled—by frequent monitoring of blood glucose and administration of insulin, the long-term complications of the disease are significant and include cardiovascular disease, nephropathy, retinopathy, and neuropathy (1). Here we revie...
متن کاملPiscine islet xenotransplantation.
Tilapia, a teleost fish species with large anatomically discrete islet organs (Brockmann bodies; BBs) that can be easily harvested without expensive and fickle islet isolation procedures, make an excellent donor species for experimental islet xenotransplantation research. When transplanted into streptozotocin-diabetic nude or severe combined immunodeficient mice, BBs provide long-term normoglyc...
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Like all plants, trees constantly monitor endogenous and environmental cues, and use this information to make adjustments in resource allocation, both to maximize resource acquisition and to minimize exposure to deleterious phenomena. To accomplish this, trees possess mechanisms that integrate and interpret the information provided by internal and environmental signals. Ultimately, these phenom...
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ژورنال
عنوان ژورنال: Journal of Clinical Investigation
سال: 1996
ISSN: 0021-9738
DOI: 10.1172/jci118911