ISIRGAN OTU (URTICA DIOICA) SULU EKSTRAKTININ SALMONELLA ENTERICA SEROVARLARININ BİYOFİLM OLUŞUMU ÜZERİNE ANTİMİKROBİYEL ETKİSİNİN BELİRLENMESİ

Due to health concerns associated with the increase of antimicrobial resistance in foodborne pathogens such as Salmonella, plant extracts have become important natural alternatives known antimicrobials. The eradication effect water-soluble stinging nettle 2 mg/mL, 4 6 8 12 16 and 20 mg/mL concentrations, on pre-formed biofilms swimming motility Salmonella enterica subspecies serovars, including Newport, Typhimurium, Enteritidis, Virchow, Othmarschen Mikawasima, was investigated vitro. Degradation biofilm formation spinach inoculated each serovar ascertained within different exposure time 40 concentrated extract well. Moreover, major genes responsible for (i.e., rpoS, mlrA, ycfR, fimA, spiA csgA) were screened these isolates. significantly decreased motilities Mikawasima Virchow serovars. highest reductions found 0.88 Log CFU/mL 2.00 CFU/cm2 vitro spinach, respectively.