Is quetiapine suitable for treatment of acute schizophrenia with catatonic stupor? A case series of 39 patients

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Is quetiapine suitable for treatment of acute schizophrenia with catatonic stupor? A case series of 39 patients

PURPOSE We aimed to determine which antipsychotic is most effective for the treatment of acute schizophrenia with catatonic stupor. PATIENTS AND METHODS Data were obtained from the medical records of 450 patients with the diagnosis of schizophrenia, who had received acute psychiatric inpatient treatment between January 2008 and December 2010 at our hospital. Among them, 39 patients (8.7%) met...

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Catatonic states do not always signify a psychiatric illness and may be a manifestation of an tmderlying medical or neurological illness. To assume that a patient who presents with a catatonic disorder must have exclusively a psychiatric disorder can lead to errors in diagnosis and management. Obvious physical illnesses such as epilepsy are easy to recognize but many subtle one? give rise to di...

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DFT calculations on quetiapine hemifumarate as a pharmaceutical compound for the treatment of schizophrenia

In this work, the optimization calculations were carried out on quetiapine hemifumarat, 4, and its analogues, 1-5. These calculations were carried out using the B3LYP/6-31G(d) level of theory. The DFT calculations clarified a boat structure for dibenzothiazepine moiety of the molecule which piperazine moiety has a chair conformation. Thermal energies (E), enthalpies (H), and free energies (G) o...

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ژورنال

عنوان ژورنال: Neuropsychiatric Disease and Treatment

سال: 2013

ISSN: 1176-6328

DOI: 10.2147/ndt.s52311