Is Kleine-Levin syndrome a variant of bipolar disorder? An hypothesis

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Is Kleine-Levin syndrome a variant of bipolar disorder? An hypothesis

Kleine-Levin syndrome (KLS) was first described in 1862 by Brierre de Boismont and gained its eponymous name from the reports of Willi Kleine (1) and Max Levin (2) in the 1920s. It is a rare disorder that occurs worldwide and is characterised by episodes of sleep, behavioural, mood and cognitive disturbance, with usually an onset in adolescence and a variable episodic course. The focus on hyper...

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Kleine-Levin syndrome: a review

Kleine-Levin syndrome is a recurrent hypersomnia associated with symptoms of hyperphagia, hypersexuality, and cognitive impairment. This article reviews the current available research and describes common clinical symptoms, differential diagnosis, and acceptable workup and treatment. Although deficits have traditionally been thought to resolve between episodes, functional imaging studies and lo...

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Kleine–Levin Syndrome: A case report☆

Kleine-Levin Syndrome is an unusual sleep disorder occurring predominantly, but not exclusively, in late adolescent males. A case is described which illustrates some of the difficulties in diagnosis and management.

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A case of Kleine-Levin syndrome.

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Differential Diagnosis of Kleine-Levin Syndrome

Investigators at Pitie-Salpetriere and Robert Debre Hospitals, and other centers in France, evaluated consecutive patients referred for suspected Kleine-Levin (KLS) syndrome, detailed differential diagnoses, and examined characteristics of patients with prolonged (>30 days) episodes.

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ژورنال

عنوان ژورنال: Acta Neuropsychiatrica

سال: 2008

ISSN: 0924-2708,1601-5215

DOI: 10.1111/j.1601-5215.2008.00291.x