Is Inflammation a Mitochondrial Dysfunction-Dependent Event in Fibromyalgia?
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چکیده
منابع مشابه
Mitochondrial dysfunction is a primary event in glutamate neurotoxicity.
Excitotoxic neuronal death, associated with neurodegenerative disorders and hypoxic insults, results from excessive exposure to excitatory neurotransmitters. Glutamate neurotoxicity is triggered primarily by massive Ca2+ influx arising from overstimulation of the NMDA subtype of glutamate receptors. The underlying mechanisms, however, remain elusive. We have tested the hypothesis that mitochond...
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objective(s): to understand the role of mitochondrial respiration in cisplatin sensitivity, we have employed wild-type and mitochondrial dna depleted rho0 yeast cells. materials and methods: wild type and rho0 yeast cultured in fermentable and non-fermentable sugar containing media, were studied for their sensitivity against cisplatin by monitoring growth curves, oxygen consumption, ph changes ...
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ژورنال
عنوان ژورنال: Antioxidants & Redox Signaling
سال: 2013
ISSN: 1523-0864,1557-7716
DOI: 10.1089/ars.2012.4892