Is hypertriglyceridemic very low density lipoprotein a precursor of normal low density lipoprotein?

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Is hypertriglyceridemic very low density lipoprotein a precursor of normal low density lipoprotein?

The precursor-product relationship of very low density (VLDL) and low density lipoproteins (LDL) was studied. VLDL obtained from normal (NTG) and hypertriglyceridemic (HTG) subjects was fractionated by zonal ultracentrifugation and subjected to in vitro lipolysis. The individual subfractions and their isolated lipolysis products, as well as IDL and LDL, were rigorously characterized. A striking...

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Very Low Density Lipoprotein (VLDL)

Triglyceride (TG) or more accurately triacylglycerol is simply a compound of three acyl groups (fatty acids) attached to a glycerol molecule. They are easily measured in the laboratory and reported as serum TG level: it actually refers to all of the TG that are being trafficked within all of the lipoproteins that exist in a deciliter of plasma. A physiologic fasting TG concentration is on avera...

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Conversion of human low density lipoprotein into a very low density lipoprotein-like particle in vitro.

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ژورنال

عنوان ژورنال: Journal of Lipid Research

سال: 1985

ISSN: 0022-2275

DOI: 10.1016/s0022-2275(20)34385-6