Is Diabetic Male Fertility Associated With Y- Chromosome Microdeletion? A Pilot Study
نویسندگان
چکیده
منابع مشابه
Correlation between Y chromosome microdeletion and male infertility.
Dyszoospermia due to genetic factors is the leading cause of male infertility. To explore the correlation between azoospermia factor (AZF) microdeletion of the Y chromosome and male infertility, we evaluated AZF microdeletion on the long arm of the Y chromosome in 166 infertile males and 50 fertile males using multiplex polymerase chain reactions amplification and gel electrophoresis. The resul...
متن کاملis karyotyping and y chromosome microdeletion study necessary in men candidate for icsi?
background: the sperm count and function may be affected by karyotype abnormalities or microdeletion in y chromosome. these genetic abnormalities can probably transmit to the children. objective: in this study, we tried to determine the frequency of karyotype abnormalities and y chromosome microdeletions in severe oligospermic or azoospermic men who fathered sons by icsi. materials and methods:...
متن کاملThe Y chromosome and male fertility and infertility.
Since 1995, thanks to a large number of studies, Y chromosome microdeletion screening has become part of the routine diagnostic work-up of severe male factor infertility. Many initial contradictory issues such as variability in deletion frequency, markers to be tested, presence of deletions in 'fertile' men, and genotype-phenotype correlation has been resolved. Past and present unresolved issue...
متن کاملA male pseudohermaphrodite with a dicentric Y chromosome. Autoradiographic study.
A 13-year-old male pseudohermaphrodite (mixed gonadal dysgenesis, unilateral testicular differentiation) was found to be a chromosomal mosaic of the 45, X0/46, XY type, the Y chromosome being a symmetrical dicentric chromosome. Presumed ¥ chromosomes similar to this one have been observed before, but their identification was not supported by autoradiographic data. In the present study the ident...
متن کاملLoss of the AZFc region due to a human Y-chromosome microdeletion in infertile male patients.
Infertility is a major reproductive health threat; the frequency of male infertility due to Y-chromosome microdeletions is 13-18% in the human population; these microdeletions involve recurrent loss of three non-overlapping regions designated as AZFa, AZFb and AZFc, associated with spermatogenic failure. Several contradictory reports have been published regarding deletion frequency based on seq...
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ژورنال
عنوان ژورنال: Journal of Fertilization: In Vitro - IVF-Worldwide, Reproductive Medicine, Genetics and Stem Cell
سال: 2014
ISSN: 2375-4508
DOI: 10.4172/2375-4508.1000149