Is 3-D Dead (Again)?

R&D productivity rides again?

A recent analysis of R&D productivity suggests that there are grounds for 'cautious optimism' that the industry 'turned the corner' in 2008 and is 'on the comeback trail'. We believe that this analysis is flawed and most probably wrong. We present an alternative analysis of these same data to suggest that the industry is not yet 'out of the woods' and suggest that many of the systemic issues af...

Shale is here again.

What do we know about ageing at work? Evidence-based fitness for duty and health in fire fighters. The current enthusiasm for fracking takes me back to the oil crisis of the late 1970s. I had been asked to see a post-thoracotomy patient and, when he recovered, found that his lesion had been pneumoconiotic. When I enquired which mine he worked in, he told me that it had been a shale mine and sin...

The brain is not dead when the cortex is dead.

To the Editor: In a recent issue of Critical Care Medicine, with interest we read the article by Dhanani et al (1), concerning vital signs after circulatory arrest following withdrawal of lifesustaining therapy. The article has timely given the persistent controversy regarding criteria of death in circulatory death organ donors. How many minutes after circulatory arrest can we consider the pati...

What is Presupposition Accommodation , Again ? ∗

Ketamine-What Is Old Is New Again.