Irreversible modification of sodium channel inactivation in toad myelinated nerve fibres by the oxidant chloramine-T.
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چکیده
منابع مشابه
Removal of sodium channel inactivation in squid axon by the oxidant chloramine-T
We have investigated the effects of a mild oxidant, chloramine-T(CT), on the sodium and potassium currents of squid axons under voltage-clamp conditions. Sodium channel inactivation of squid giant axons can be completely removed by CT at neutral pH. Internal and external CT treatment are both effective. CT apparently removes inactivation in an irreversible, all-or-none manner. The activation pr...
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ژورنال
عنوان ژورنال: The Journal of Physiology
سال: 1984
ISSN: 0022-3751
DOI: 10.1113/jphysiol.1984.sp015011