IRP2 Regulates Breast Tumor Growth
نویسندگان
چکیده
منابع مشابه
IRP2 regulates breast tumor growth.
Experimental and epidemiologic evidence suggests that dysregulation of proteins involved in iron metabolism plays a critical role in cancer. The mechanisms by which cancer cells alter homeostatic iron regulation are just beginning to be understood. Here, we demonstrate that iron regulatory protein 2 (IRP2) plays a key role in iron accumulation in breast cancer. Although both IRP1 and IRP2 are o...
متن کاملMolecular and Cellular Pathobiology IRP2 Regulates Breast Tumor Growth
Experimental and epidemiologic evidence suggests that dysregulation of proteins involved in ironmetabolism plays a critical role in cancer. The mechanisms by which cancer cells alter homeostatic iron regulation are just beginning to be understood. Here, we demonstrate that iron regulatory protein 2 (IRP2) plays a key role in iron accumulation in breast cancer. Although both IRP1 and IRP2 are ov...
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ژورنال
عنوان ژورنال: Cancer Research
سال: 2013
ISSN: 0008-5472,1538-7445
DOI: 10.1158/0008-5472.can-13-1224