Iron deficiency in pulmonary arterial hypertension: perspectives

In left heart failure, iron supplementation (IS) is a first-line treatment option, regardless of anemia. Pulmonary arterial hypertension (PAH), rare disease leading to right also associated with deficiency. While it much debated topic, recent evidence demonstrate that restoration stores results in improved ventricular function and exercise tolerance. Hence, IS may be considered as an option the PAH.