Iron bioavailability and cardiopulmonary function during ascent to very high altitude
نویسندگان
چکیده
منابع مشابه
Effect of acetazolamide on blood gases and 2,3 DPG during ascent and acclimatization to high altitude.
Blood gases and red cell 2,3 DPG concentrations were measured during ascent and a stay for 6 days at 4846 m in 20 subjects. Acetazolamide improved Pa,O2 and reduced pH and Pa,CO2. 2,3 DPG concentrations were lower in the acetazolamide group during ascent and at high altitude. However, 2,3 DPG concentrations were significantly greater at high altitude in both the acetazolamide and placebo groups...
متن کاملEffects of Ascent to High Altitude on Human Antimycobacterial Immunity
BACKGROUND Tuberculosis infection, disease and mortality are all less common at high than low altitude and ascent to high altitude was historically recommended for treatment. The immunological and mycobacterial mechanisms underlying the association between altitude and tuberculosis are unclear. We studied the effects of altitude on mycobacteria and antimycobacterial immunity. METHODS Antimyco...
متن کاملThromboelastometry and Platelet Function during Acclimatization to High Altitude.
Interaction between hypoxia and coagulation is important given the increased risk of thrombotic diseases in chronically hypoxic patients who reside at sea level and in residents at high altitude. Hypoxia alters the proteome of platelets favouring a prothrombotic phenotype, but studies of activation and consumption of specific coagulation factors in hypoxic humans have yielded conflicting result...
متن کاملThe impact of moderate-altitude staging on pulmonary arterial hemodynamics after ascent to high altitude.
Staged ascent (SA), temporary residence at moderate altitude en route to high altitude, reduces the incidence and severity of noncardiopulmonary altitude illness such as acute mountain sickness. To date, the impact of SA on pulmonary arterial pressure (PAP) is unknown. We tested the hypothesis that SA would attenuate the PAP increase that occurs during rapid, direct ascent (DA). Transthoracic e...
متن کاملIntraocular pressure during a very high altitude climb.
PURPOSE Reports on intraocular pressure (IOP) changes at high altitudes have provided inconsistent and even conflicting RESULTS The purpose of this study was to investigate the effect of very high altitude and different ascent profiles on IOP in relation to simultaneously occurring ophthalmic and systemic changes in a prospective study. METHODS This prospective study involved 25 healthy mou...
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ژورنال
عنوان ژورنال: European Respiratory Journal
سال: 2020
ISSN: 0903-1936,1399-3003
DOI: 10.1183/13993003.02285-2019