Ion-exchange membrane assisted transdermal iontophoretic delivery of salicylate and acyclovir
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چکیده
منابع مشابه
The Use of Ion-exchange Fibers in Controlled Transdermal Iontophoretic Drug Delivery
Transdermal iontophoresis is a method where the movement of ionic drugs (and sometimes also neutral drug molecules) across skin is enhanced using an externally applied potential difference. Iontophoretic devices contain three distinct components; 1) the drug reservoir which contains one electrode, the polarity chosen depends on the charge of the drug, 2) the return electrode and 3) the electron...
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Transdermal iontophoresis would be a promising method for the systemic delivery of water soluble and ionic drugs of relatively high molecular size, including peptides. The objective of the present study was to investigate the effect of biological variable such as guinea pig and human cadaver skin and other variables like drug concentration, current density on the transdermal iontophoretic trans...
متن کاملControlled Transdermal Drug Delivery by Iontophoresis and Ion-exchange Fiber
Kankkunen, T., 2002. Controlled transdermal drug delivery by iontophoresis and ionexchange fiber. Dissertationes Biocentri Viikki Universitatis Helsingiensis 17/2002, pp. 57 ISBN 952-10-0313-8 (print) ISBN 952-10-0314-6 (pdf) ISSN 1239-9469 A common aim in the development of new transdermal devices is the controlled delivery of drugs, so that the rate of drug input into the blood stream is pred...
متن کاملIontophoretic and Microneedle Mediated Transdermal Delivery of Glycopyrrolate
PURPOSE The objective of this study was to investigate the use of iontophoresis, soluble microneedles and their combination for the transdermal delivery of glycopyrrolate. METHODS In vitro permeation was tested using full thickness porcine ear skin mounted onto Franz diffusion cells. Iontophoresis (0.5 mA/cm2) was done for 4 h using Ag/AgCl electrodes. For microneedles, three line array (27 n...
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........................................................................................................................................ ii Acknowledgments........................................................................................................................ iii List of Tables .........................................................................................................
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ژورنال
عنوان ژورنال: International Journal of Pharmaceutics
سال: 2009
ISSN: 0378-5173
DOI: 10.1016/j.ijpharm.2008.11.001