Involvement of Extracellular Signal-Regulated Kinase in Nobiletin-Induced Melanogenesis in Murine B16/F10 Melanoma Cells
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منابع مشابه
Zeolite 4A, a synthetic silicate, suppresses melanogenesis through the degradation of microphthalmia-associated transcription factor by extracellular signal-regulated kinase activation in B16F10 melanoma cells.
Zeolite 4A, synthetic silicate, has been shown to exhibit diverse biological activities such as anti-cancer and anti-oxidant activity. In the present study, we report that the zeolite 4A may improve skin-whitening. We found that zeolite 4A inhibited melanin production in a dose-dependent manner, which has not cytotoxicity. Zeolite 4A also inhibited alpha-melanocyte-stimulating hormone (alpha-MS...
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Recent studies have shown that plumbagin has anti-inflammatory, anti-allergic, antibacterial, and anti-cancer activities; however, it has not yet been shown whether plumbagin suppresses alpha-melanocyte stimulating hormone (α-MSH)-induced melanin synthesis to prevent hyperpigmentation. In this study, we demonstrated that plumbagin significantly suppresses α-MSH-stimulated melanin synthesis in B...
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Objective(s): In previous studies, antioxidant activity of Viola odorata L. has been demonstrated. In this study, we have investigated the anti-melanogenic effect of extract and fractions of the plant in B16F10 cell line. Materials and Methods: Impact of different increasing concentrations of extract and fractions of V. odorata was evaluated on cell viability, cellular tyrosinase, melanin conte...
متن کاملCAteChOlAMInes InCReAse In vItRO pROlIfeRAtIOn Of MuRIne B16f10 MelAnOMA Cells
545 Acta Endocrinologica (Buc), vol. X, no. 4, p. 545-558, 2014 *Correspondence to: Daniel Boda MD, PhD, “Carol Davila” University of Medicine and Pharmacy Dermatology Research Laboratory, 22-24 Gr. Manolescu, Sector 1, Bucharest, 0111234, Romania, E-mail: [email protected] Abstract Context. Melanoma is the most aggressive skin cancer, with significant morbidity and mortality, and one facto...
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ژورنال
عنوان ژورنال: Bioscience, Biotechnology, and Biochemistry
سال: 2007
ISSN: 0916-8451,1347-6947
DOI: 10.1271/bbb.70088