Investigation of MTHFR gene C677T polymorphism in cardiac syndrome X patients
نویسندگان
چکیده
منابع مشابه
Hyperhomocysteinaemia and MTHFR C677T gene polymorphism in renal transplant recipients.
AIM To study the effect of folate treatment on hyperhomocysteinaemia and the effect of 5,10-methylenetetrahydrofolate reductase (MTHFR) gene polymorphism on total homocysteine and folate concentrations after renal transplantation. METHODS A total of 30 transplanted children and adolescents were investigated for total homocysteine and folate serum concentrations before and after folate treatme...
متن کاملMTHFR Gene C677T Polymorphism in Autism Spectrum Disorders
Aim. Autism is a subgroup of autism spectrum disorders, classified as a heterogeneous neurodevelopmental disorder and symptoms occur in the first three years of life. The etiology of autism is largely unknown, but it has been accepted that genetic and environmental factors may both be responsible for the disease. Recent studies have revealed that the genes involved in the folate/homocysteine pa...
متن کاملInvestigating the methylation status of DACT2 gene and its association with MTHFR C677T polymorphism in patients with colorectal cancer
Colorectal cancer (CRC) is one of the common causes of cancer death in Iranian population. Both genetic and epigenetic changes have been implicated in CRC pathogenesis. DACT2 gene as one of the WNT signaling pathway inhibitor was shown to display tumor suppressor activity in many cancers. The aim of present study was to investigate the methylation status of DACT2 gene and its ...
متن کاملC677T (RS1801133 ) MTHFR gene polymorphism frequency in a colombian population
INTRODUCTION Abnormal levels of the enzyme methylenetetrahydrofolate reductase (MTHFR) are associated with an increased risk of both cardiovascular and cerebrovascular disease and higher concentrations of homocysteine. Abnormal levels are also related to birth defects, pregnancy complications, cancer and toxicity to methotrexate (MTX). Polymorphisms of MTHFR affect the activity of the enzyme. G...
متن کاملAssociation of the MTHFR C677T polymorphism and fragile X syndrome in an Iranian population
Background & Objective: Fragile X syndrome is one of the most common causes of inherited mental retardation in males after Down syndrome. To date less attention was to study secondary genetic factor that may play role in fragile X neuropathology. In central nervous system, folic acid derivatives participate in different process such as neural development and function, synthesis of neurotransmit...
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ژورنال
عنوان ژورنال: Journal of Clinical Laboratory Analysis
سال: 2017
ISSN: 0887-8013
DOI: 10.1002/jcla.22247