Intravenous thiotepa for treatment of leptomeningeal carcinomatosis: Retrospective case series
نویسندگان
چکیده
منابع مشابه
Recent Advancements of Treatment for Leptomeningeal Carcinomatosis
Treatment of Leptomeningeal carcinomatosis (LMC) from solid cancers has not advanced noticeably since the introduction of intra-cerebrospinal fluid (CSF) chemotherapy in the 1970's. The marginal survival benefit and difficulty of intrathecal chemotherapy injection has hindered its wide spread use. Even after the introduction of intraventricular chemotherapy with Ommaya reservoir, frequent devel...
متن کاملA case of metastatic leptomeningeal carcinomatosis from early gastric carcinoma
Metastatic leptomeningeal carcinomatosis is estimated to occur in 3% to 8% of solid carcinomas. The most common causes of leptomeningeal carcinomatosis are breast cancer, lung cancer and malignant melanoma. Leptomeningeal carcinomatosis associated with gastric cancer, especially in its early stages, is exceedingly rare. Its presenting symptoms include headache, nausea and seizures. In this repo...
متن کاملTreatment of Leptomeningeal Carcinomatosis in a Patient With Metastatic Cholangiocarcinoma
A 49-year-old woman with cholangiocarcinoma metastatic to the lungs presented with new-onset unrelenting headaches. A lumbar puncture revealed malignant cells consistent with leptomeningeal metastasis from her cholangiocarcinoma. Magnetic resonance imaging (MRI) of the brain revealed leptomeningeal enhancement. An intrathecal (IT) catheter was placed and IT chemotherapy was initiated with metho...
متن کاملa report of a rare gastric cancer case: leptomeningeal carcinomatosis
leptomeningeal carcinomatosis (lmc) from gastrointestinal cancer would be rare. a 56-years old man with complaint of dyspepsia and histopathologic examination of the biopsy specimens has shown: adenocarcinoma. at the end of adjuvant chemo radiation therapy, the patient has affected by headache and mild confusion. in cerebrospinal fluid (csf) cytology, a plenty of malignant cells have seen and u...
متن کاملA Report of a Rare Gastric Cancer Case: Leptomeningeal Carcinomatosis
Leptomeningeal carcinomatosis (LMC) from gastrointestinal cancer would be rare. A 56-years old man with complaint of dyspepsia and histopathologic examination of the biopsy specimens has shown: adenocarcinoma. At the end of adjuvant chemo radiation therapy, the patient has affected by headache and mild confusion. In cerebrospinal fluid (CSF) cytology, a plenty of malignant cells have seen and u...
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ژورنال
عنوان ژورنال: Annals of Oncology
سال: 2015
ISSN: 0923-7534
DOI: 10.1093/annonc/mdv115.05