Intravenous Anaesthesia: Steroids

Total Intravenous Anaesthesia (tiva) and Partial Intravenous Anaesthesia (piva)

Hazards of steroids in association with anaesthesia.

SHOCK OR HYPOTENSION under operative stress due to adrenal failure following steroid therapy is now well recognized. 1-~ Confirmation that such episodes are attributable to adrenal failure can come only from a study of plasma cortisol levels during shock or hypotension. Direct evidence of this has been scanty and difficult to acquire. There are several points to be resolved: (a) Do we frequentl...

Recent advances in intravenous anaesthesia.

Efforts to develop new hypnotic compounds continue, although several have recently failed in development. Propofol has been reformulated in various presentations with and without preservatives. Pharmacokinetic and pharmacodynamic differences exist between some of these preparations, and it is currently unclear whether any have substantial advantages over the original presentation. The use of ta...

Recent advances in intravenous anaesthesia

Efforts to develop new hypnotic compounds continue, although several have recently failed in development. Propofol has been reformulated in various presentations with and without preservatives. Pharmacokinetic and pharmacodynamic differences exist between some of these preparations, and it is currently unclear whether any have substantial advantages over the original presentation. The use of ta...

Total intravenous anaesthesia in children

The use of total intravenous anaesthesia (TIVA) in children has become a popular technique for the induction and maintenance of anaesthesia following the introduction of newer short-acting drugs and more elaborate delivery systems. Advances in microprocessor technology and increased complexity of pharmacokinetic modelling have further refined TIVA to target controlled infusions (TCI). TCI deliv...