Intravascular radiation for restenosis prevention: could it be the holy grail?

Intravascular radiation for restenosis prevention: could it be the holy grail?

CGRP antibodies: the Holy Grail for migraine prevention?

Searching for the Holy Grail?

Pursuing the "Holy Grail".

Over the past decade, several large, randomized trials have allowed us to better define the appropriate population for primary prevention implantable cardioverterdefibrillator (ICD) placement, saving thousands of lives every year. MADIT II (Multicenter Automatic Defibrillator Implantation Trial II) and SCD-HeFT (Sudden Cardiac Death in Heart Failure Trial) have demonstrated a survival benefit o...

Bisphosphonates for osteoarthritis prevention: "Holy Grail" or not?

The search for effective disease modifying osteoarthritis (OA) agents has been a long and winding road with much unrealised promise. While a debate persists about whether OA is predominately a disease of bone, cartilage, or both, there has been interest in the possible OA disease modifying effects of bone antiresorptive agents including oestrogens, selective oestrogen receptor modulators, calci...